Porcine prothrombin is prepared from pig plasma by a proprietary combination of precipitations and conventional chromatography. Porcine prothrombin (Factor II) is a glycoprotein of molecular weight 72,000, and consists of a single polypeptide chain. Activation of prothrombin by Factor Va, Xa and phospholipids yields the serine protease thrombin. Prothrombin purity is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol.
Gene ID: 100144442
Swiss-Prot/UniProt ID: Q19AZ8