PAI-1 Knockin Mice


SKU: MS-PAI-R124A Category:

Product Description

PAI-1 Knockin Mice

This Plasminogen Activator Inhibitor-1 (PAI-1) knockin mouse model was created by targeted substitution of critical amino acids using programed nuclease. A single amino acid point mutation results in PAI-1 with reduced binding to the serum protein vitronectin. These vitronectin binding deficient mice are in breeding now and homozygous mice will be available soon.

Strain Background: C57BL6/SJL
Chromosome: 5
Gene: Serpine1
Protein: Plasminogen Activator Inhibitor-1
Synonyms: PAI-1
Genomic Target: Exon 2
Mutation: Arg124->Ala

Our mutant mice are from an ongoing colony made in-house at our state of the art facility in the U.S.A and available immediately. No waiting for cryo recovery or costly breeding.

Click here to view more PAI-1 related products.

We also provide custom Mouse Model projects and offer FREE consulting services from our expert scientific staff along with very competitive pricing. Click here to inquire.

Click here to read our recent research model report. Click here to learn more about all the various knockout and knockin mouse models we offer.

You may also like…