Mouse PAI-1 tPA complex

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Product Description

Mouse PAI-1 tPA complex

Mouse sc-tPA is reacted with an excess of mouse PAI-1 stable mutant at physiological pH. The resulting 1:1 molar complex is purified from the remaining PAI-1 by affinity chromatography with immobilized antibodies to mouse tPA.

Gene ID: 18787, 18792
Swiss-Prot/UniProt ID: P22777, P06869

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1. Sashindranath M, Sales E, Daglas M et-al. The tissue-type plasminogen activator-plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans. Brain. 2012;135 (Pt): 3251-64. doi:10.1093/brain/aws178Free text at pubmedPubmed citation