Mouse monoclonal to mouse uPA

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Product Description

Mouse monoclonal to mouse uPA

Capture monoclonal antibody produced in mouse. IgG fraction purified by immobilized Protein A. Clone H77A10, isotype IgG.

Gene ID: 18792
Swiss-Prot/UniProt ID: P06869

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1. Shushakova N, Eden G, Dangers M et-al. The urokinase/urokinase receptor system mediates the IgG immune complex-induced inflammation in lung. J. Immunol. 2005;175 (6): 4060-8. J. Immunol. (link)Pubmed citation

2. Merchan JR, Tang J, Hu G et-al. Protease activity of urokinase and tumor progression in a syngeneic mammary cancer model. J. Natl. Cancer Inst. 2006;98 (11): 756-64. doi:10.1093/jnci/djj208Pubmed citation

3. Botkjaer KA, Deryugina EI, Dupont DM et-al. Targeting tumor cell invasion and dissemination in vivo by an aptamer that inhibits urokinase-type plasminogen activator through a novel multifunctional mechanism. Mol. Cancer Res. 2012;10 (12): 1532-43. doi:10.1158/1541-7786.MCR-12-0349Free text at pubmedPubmed citation

4. Andersen LM, Wind T, Hansen HD, Andreasen PA. A cyclic peptidylic inhibitor of murine urokinase-type plasminogen activator: changing species specificity by substitution of a single residue. Biochem J. 2008;412(3):447-57. Link to article

5. Li SH, Gorlatova NV, Lawrence DA et-al. Structural differences between active forms of plasminogen activator inhibitor type 1 revealed by conformationally sensitive ligands. J. Biol. Chem. 2008;283 (26): 18147-57. doi:10.1074/jbc.M709455200Free text at pubmedPubmed citation

6. Apparailly F, Bouquet C, Millet V, et al. Adenovirus-mediated gene transfer of urokinase plasminogen inhibitor inhibits angiogenesis in experimental arthritis. Gene Ther. 2002;9(3):192-200. Link to article

7. Chintala SK. Tissue and urokinase plasminogen activators instigate the degeneration of retinal ganglion cells in a mouse model of glaucoma. Exp Eye Res. 2016;143:17-27. Link to article

8. Frau E, Magnon C, Opolon P, et al. A gene transfer comparative study of HSA-conjugated antiangiogenic factors in a transgenic mouse model of metastatic ocular cancer. Cancer Gene Ther. 2007;14(3):251-61. Link to article