Product Description
Inhibitory mouse monoclonal to mouse PAI-1 clone H4B3
Inhibitory monoclonal antibody produced in mouse. It binds to a conformational epitope on recombinant non-glycosylated PAI-1 converting it to the latent form in a time-dependent manner. IgG fraction purified by immobilized Protein A. Isotype IgG.
References:
Evidence for a Pre-latent Form of the Serpin Plasminogen Activator Inhibitor-1 with a Detached B-Strand 1C. Dupont DM et al. Journal of Biological Chemistry 281, 36071–36081 (2006).
Gene ID: 18787
Swiss-Prot/UniProt ID: P22777
View sample datasheet
View sample certificate of analysis
View material safety data sheet
Ask a question about this product
Like this:
Like Loading...
1. Cambier S, Gline S, Mu D et-al. Integrin alpha(v)beta8-mediated activation of transforming growth factor-beta by perivascular astrocytes: an angiogenic control switch. Am. J. Pathol. 2005;166 (6): 1883-94. Am. J. Pathol. (link) – Free text at pubmed – Pubmed citation
2. Scroyen I, Christiaens V, Lijnen HR. No functional role of plasminogen activator inhibitor-1 in murine adipogenesis or adipocyte differentiation. J. Thromb. Haemost. 2007;5 (1): 139-45. doi:10.1111/j.1538-7836.2006.02284.x – Pubmed citation
3. Riehl TE, He L, Zheng L et-al. COX-1(+/-)COX-2(-/-) genotype in mice is associated with shortened time to carotid artery occlusion through increased PAI-1. J. Thromb. Haemost. 2011;9 (2): 350-60. doi:10.1111/j.1538-7836.2010.04156.x – Free text at pubmed – Pubmed citation
4. Fjellström O, Deinum J, Sjögren T et-al. Characterization of a small molecule inhibitor of plasminogen activator inhibitor type 1 that accelerates the transition into the latent conformation. J. Biol. Chem. 2013;288 (2): 873-85. doi:10.1074/jbc.M112.371732 – Free text at pubmed – Pubmed citation
Like this:
Like Loading...
