Inhibitory mouse monclonal to mouse antiplasmin clone 4H9
Inhibitory monoclonal antibody produced in an alpha-2-antiplasmin knockout mouse. Neutralizes 60 percent of mouse antiplasmin in equimolar mixtures as determined by in vitro chromogenic plasmin activity assay. IgG3K fraction purified by immobilized Protein A. Clone 4H9, isotype IgG3 kappa.
Depletion of circulating a2-antiplasmin by intravenous plasmin or immunoneutralization reduces focal cerebral ischemic injury in the absence of arterial recanalization. Nagai M et al. Blood 97, 3086-3092 (2001).