Inhibitory Anti-Human Prothrombin
Clone number AHP-5013. Reactive to: Human prothrombin, prethrombin-1, fragment 2, meizothrombin. Does not recognize mouse thrombin by western blot. Inhibits clotting and prothrombin activation. Clotting inhibition was determined by incubating the antibody with human normal pooled plasma followed by a PT assay. Extension of the clot time reflects inhibition of the clotting. The inhibition of the prothrombin activation was determined in prothrombinase reactions using purified clotting factors and DAPA as a substrate for thrombin. IgG fraction purified by conventional chromatography. Mouse monoclonal of isotype IgG2a.