$250 – $1,180
Human alpha-thrombin is prepared from purified prothrombin by activation with coastal taipan venom followed by affinity chromatography. Purity is verified by SDS-PAGE analysis and specific activity in NIH thrombin units is determined by chromogenic substrate.
Gene ID: 2147
Swiss-Prot/UniProt ID: P00734
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1. Middendorp SJ, Wilbs J, Quarroz C, Calzavarini S, Angelillo-scherrer A, Heinis C. Peptide Macrocycle Inhibitor of Coagulation Factor XII with Subnanomolar Affinity and High Target Selectivity. J Med Chem. 2017;60(3):1151-1158. Link to article
2. Swedberg JE, Li CY, De veer SJ, Wang CK, Craik DJ. Design of Potent and Selective Cathepsin G Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold. J Med Chem. 2017;60(2):658-667. Link to article
3. De veer SJ, Li CY, Swedberg JE, Schroeder CI, Craik DJ. Engineering potent mesotrypsin inhibitors based on the plant-derived cyclic peptide, sunflower trypsin inhibitor-1. Eur J Med Chem. 2018;155:695-704. Link to article
4. Lira AL. Allosteric inhibition of a-thrombin enzymaticactivity with ultrasmall gold nanoparticles. Nanoscale Advances. September 2018. Link to article
