High Affinity Heparin
Heparin is a naturally occurring glycosaminoglycan that acts as an anticoagulant by accelerating the inhibition of thrombin and Factor Xa by antithrombin III. High affinity heparin contains a specific pentasaccharide sequence required for binding to antithrombin. Useful for haemostasis mechanistic studies. High affinity heparin from Molecular Innovations is purified using immobilized antithrombin and supplied as a salt free lyophilized powder.
Steven T. Olson, Ingemar Bjork, and Joseph D. Shore. Kinetic Characterization of Heparin-Catalyzed and Uncatalyzed Inhibition of Blood Coagulation Proteinases by Antithrombin. Methods in Enzymology 1993, 222: 525-559.