Fluorescein Labeled Phe-Pro-Arg-Chloromethylketone
Fluorescein labeled Phe-Pro-Arg-Chloromethylketone. Extremely potent and selective irreversible inhibitor of thrombin (Kobs/[I] = 107M-1S-1). Reacts with thrombin in a 1:1 stoichiometry. Can also be used to inhibit plasmin, tissue plasminogen activator, urokinase, Factor VIIa, and Factor XIa. Also known as PPACK and Phe-Pro-Arg-CMK (FPRCK).
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