Biotinylated Thrombin


SKU: HTHROM-BIO Categories: , ,

Product Description

Biotinylated Thrombin

Biotinylated thrombin is useful for cleavage of proteins and peptides at the enzyme recognition sequence Leu-Val-Pro-Arg-||-Gly-Ser. Biotinylated thrombin is then easily removed from the reaction with immobilized avidin agarose resin. This preparation is >95% pure on SDS-PAGE and is tested for activity using thrombin chromogenic substrate and cleavage control protein.

Gene ID: 2147
Swiss-Prot/UniProt ID: P00734

View sample datasheet
View sample certificate of analysis
View material safety data sheet
Ask a question about this product

Additional Information



Molecular Weight

Extinction Coefficient



Shipping Conditions




Sample Size

Sample Concentration

Sample Volume


Gene Name

Gene ID

UniProt ID

1. Middendorp SJ, Wilbs J, Quarroz C, Calzavarini S, Angelillo-scherrer A, Heinis C. Peptide Macrocycle Inhibitor of Coagulation Factor XII with Subnanomolar Affinity and High Target Selectivity. J Med Chem. 2017;60(3):1151-1158. Link to article

2. Swedberg JE, Li CY, De veer SJ, Wang CK, Craik DJ. Design of Potent and Selective Cathepsin G Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold. J Med Chem. 2017;60(2):658-667. Link to article

3. De veer SJ, Li CY, Swedberg JE, Schroeder CI, Craik DJ. Engineering potent mesotrypsin inhibitors based on the plant-derived cyclic peptide, sunflower trypsin inhibitor-1. Eur J Med Chem. 2018;155:695-704. Link to article

4. Lira AL. Allosteric inhibition of a-thrombin enzymaticactivity with ultrasmall gold nanoparticles. Nanoscale Advances. September 2018. Link to article