Product Datasheet

 
Product Description
 
Product: Human PAI-1 substrate form P14 arginine mutant
Catalog Number: HPAI-T333R
Product Page: https://www.mol-innov.com/products/IHUPAI1RP14SB500UG
Description: A single substitution at position P14 in the reactive center loop produces a PAI-1 that becomes a substrate for proteinases rather than an inhibitor. Reactive center loop insertion follows protease cleavage and the PAI-1 loses vitronectin binding properties. This molecule is useful for mechanistic studies.
References
1. Lawrence, D.A. et al. (2000) J. Biol. Chem. 275:5839-5844.
2. Palmieri, D. et al. (2002) J. Biol. Chem. 277:40950-40957.
Recommended Storage: SAMPLE
Minimum Shelf Life: 500.50
Source: 2.5 mg/ml
Molecular Weight: Proteins
Extinction Coefficient: 43,000
Antigen: -70 C
Target: Frozen liquid
Target Molecular Weight: PAI-1
Host: 819
Clonality: 30
Isotype: E. coli
Applications: Dry ice
Cross-reactivity: 3 years from delivery
 
Sample Characteristics
 
Lot Number: HPAI-T333R-IHUPAI1RP14SB1MG
Aliquot: 1 x Human PAI-1 Recombinant P14 Arginine Mutant Substrate 1 mg
Concentration: 715
Volume: 1170
Titer: 0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6
Buffer: SAMPLE
Form: 0.5 mg
Preservative: 0.2 ml
 
Optimal experimental conditions and working dilutions must be determined by the end user. Sample concentration and volume are for example purposes only and do not necessarily represent the product that will be received. Please contact us for a current lot-specific product datasheet.
 
For in vitro laboratory use only
 
Molecular Innovations, Inc. - 46430 Peary Court, Novi, MI 48377, USA
Tel: (888) 557-5055 - Fax: (248) 896-0148 - info@mol-innov.com