Product Datasheet
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Product Description |
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Product: |
Human PAI-1 substrate form P14 arginine mutant |
Catalog Number: |
HPAI-T333R |
Product Page: |
https://www.mol-innov.com/products/IHUPAI1RP14SB500UG |
Description: |
A single substitution at position P14 in the reactive center loop produces a PAI-1 that becomes a substrate for proteinases rather than an inhibitor. Reactive center loop insertion follows protease cleavage and the PAI-1 loses vitronectin binding properties. This molecule is useful for mechanistic studies.
References
1. Lawrence, D.A. et al. (2000) J. Biol. Chem. 275:5839-5844.
2. Palmieri, D. et al. (2002) J. Biol. Chem. 277:40950-40957. |
Recommended Storage: |
SAMPLE |
Minimum Shelf Life: |
500.50 |
Source: |
2.5 mg/ml |
Molecular Weight: |
Proteins |
Extinction Coefficient: |
43,000 |
Antigen: |
-70 C |
Target: |
Frozen liquid |
Target Molecular Weight: |
PAI-1 |
Host: |
819 |
Clonality: |
30 |
Isotype: |
E. coli |
Applications: |
Dry ice |
Cross-reactivity: |
3 years from delivery |
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Sample Characteristics |
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Lot Number: |
HPAI-T333R-IHUPAI1RP14SB1MG |
Aliquot: |
1 x Human PAI-1 Recombinant P14 Arginine Mutant Substrate 1 mg |
Concentration: |
715 |
Volume: |
1170 |
Titer: |
0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6 |
Buffer: |
SAMPLE |
Form: |
0.5 mg |
Preservative: |
0.2 ml |
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Optimal experimental conditions and working dilutions must be determined by the end user. Sample concentration and volume are for example purposes only and do not necessarily represent the product that will be received. Please contact us for a current lot-specific product datasheet. |
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For in vitro laboratory use only |
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Molecular Innovations, Inc. - 46430 Peary Court, Novi, MI 48377, USA Tel: (888) 557-5055 - Fax: (248) 896-0148 - info@mol-innov.com |