Product Datasheet
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| Product Description |
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| Product: |
Recombinant human Factor beta-XIIa |
| Catalog Number: |
HFXIIAB-INS |
| Product Page: |
https://www.mol-innov.com/products/IHUFXIIABR50UG |
| Description: |
The low molecular weight beta form of human Factor XIIa is generated in vivo by kallikrein cleavage of Factor alpha-XIIa and contains the catalytic light chain and the C-terminal peptide of the heavy chain of Factor alpha-XIIa. Recombinant Human Factor beta-XIIa is activated from insect cell culture derived Factor XII by an extended autoactivation process with Dextran Sulfate followed by repurification. Complete activation is observed on SDS-PAGE. Factor XIIa activates Factor XI to XIa thereby triggering the Contact Factor cascade. The protein purity is determined by SDS-PAGE and activity is determined via complementation in an APTT clotting assay using Factor XII immuno-deficient human plasma. Specific activity of this recombinant product is typically lower than that of plasma derived material. Custom mutants of Factor XII are also available, please contact us for more details. |
| Recommended Storage: |
SAMPLE |
| Minimum Shelf Life: |
234.50 |
| Source: |
0.25 mg/ml |
| Molecular Weight: |
Proteins |
| Extinction Coefficient: |
30,000 (Human Plasma Derived) |
| Antigen: |
-70 C |
| Target: |
Frozen liquid |
| Target Molecular Weight: |
FACTOR XII |
| Host: |
423.5 |
| Clonality: |
30 |
| Isotype: |
Insect cell culture |
| Applications: |
Dry ice |
| Cross-reactivity: |
3 years from delivery |
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| Sample Characteristics |
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| Lot Number: |
HFXIIAB-INS-IHUFXIIABR100UG |
| Aliquot: |
1 x Human Factor beta-XIIa Recombinant 100ug |
| Concentration: |
335 |
| Volume: |
605 |
| Titer: |
4 mM Sodium Acetate; 0.15 M NaCl; pH 5.3 |
| Buffer: |
SAMPLE |
| Form: |
0.05 mg |
| Preservative: |
0.2 ml |
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| Optimal experimental conditions and working dilutions must be determined by the end user. Sample concentration and volume are for example purposes only and do not necessarily represent the product that will be received. Please contact us for a current lot-specific product datasheet. |
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| For in vitro laboratory use only |
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Molecular Innovations, Inc. - 46430 Peary Court, Novi, MI 48377, USA
Tel: (888) 557-5055 - Fax: (248) 896-0148 - info@mol-innov.com |