Product Datasheet
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Product Description |
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Product: |
Human PAI-1 Stable Mutant, Low Endotoxin |
Catalog Number: |
CPAI-ED |
Product Page: |
https://www.mol-innov.com/products/IHUPAI1RSMLXLY100UG |
Description: |
The human form of PAI-1 contains the following four mutations: K154T, Q319L, M354I and N150H. These mutations combine to confer great stability to the otherwise labile molecule essentially locking in into the active conformation. It is an ideal choice for in vivo and cell culture studies. This preparation is purified to lower levels of endotoxin (<0.01 EU/ug) and does not contain animal carrier proteins or sodium azide. It is lyophilized and fully active. Add sterile endotoxin free deionized water to original volume or PAI-1 storage buffer (0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6) to desired volume. Aliquot and freeze unused portion. |
Recommended Storage: |
SAMPLE |
Shipping Conditions: |
>95% active by uPA titration; Second order rate constant for inhibition of uPA = 5.1 X 10^6 M-1s-1, tPA = 7.9 X 10^5 M-1s-1 |
Minimum Shelf Life: |
420.00 |
Source: |
Lyophilized |
Molecular Weight: |
Proteins |
Extinction Coefficient: |
43,000 |
Antigen: |
-20 C |
Target: |
Lyophilized powder |
Target Molecular Weight: |
PAI-1 |
Host: |
1680 |
Clonality: |
30 |
Isotype: |
E. coli |
Clone: |
s |
Applications: |
Cold pack |
Cross-reactivity: |
3 years from delivery |
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Sample Characteristics |
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Lot Number: |
CPAI-ED-IHUPAI1RSMLXLY500UG |
Aliquot: |
1 x Human PAI-1 Recombinant Stable Mutant Low Endotoxin Lyophilized 500ug |
Concentration: |
600 |
Volume: |
2400 |
Titer: |
0.0067M Phosphate; 0.15M NaCl; pH 7.4 |
Buffer: |
19-Aug |
Form: |
0.1 mg |
Preservative: |
1.0 ml before lyophilization |
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Optimal experimental conditions and working dilutions must be determined by the end user. Sample concentration and volume are for example purposes only and do not necessarily represent the product that will be received. Please contact us for a current lot-specific product datasheet. |
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For in vitro laboratory use only |
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Molecular Innovations, Inc. - 46430 Peary Court, Novi, MI 48377, USA Tel: (888) 557-5055 - Fax: (248) 896-0148 - info@mol-innov.com |