tPA Specific Human PAI-1

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SKU: HPAI-YSY Categories: ,

Product Description

A triple mutation on the wild-type background makes this Human PAI-1 selectively inhibit tPA. Urokinase inhibition is limited to 1/25,000 of tPA inhibition by the P3Tyr-P2Ser-P1Tyr mutation.

References:
Sherman PM. et al. (1995) J Biol Chem 270:9301-9306.

Gene ID: 5054
Swiss-Prot/UniProt ID: P05121

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