tPA Knockout Mice
This Tissue Plasminogen Activator (tPA) knockout mouse model was created by targeted disruption of Plat using programed nuclease. Mutations are confirmed by PCR genotyping and Sanger sequencing. Heterozygous mice are in breeding now and homozygous mice will be available soon. This tPA KO mouse model will be useful for cardiovascular and neurological studies.
Strain background: C57B6SJL
Protein: Tissue Plasminogen Activator
Targeted Exon: Exon 4
Mutation: Large deletion
Our mutant mice are from an ongoing colony made in-house at our state of the art facility in the U.S.A and available immediately. No waiting for cryo recovery or costly breeding.
We also provide custom Mouse Model projects and offer FREE consulting services from our expert scientific staff along with very competitive pricing. Click here to inquire.