Rabbit anti mouse PAI-1 IgG fraction

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Product Description

Rabbit anti mouse PAI-1 IgG fraction

Polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.

Gene ID: 18787
Swiss-Prot/UniProt ID: P22777

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Additional Information

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1. Weisberg AD, Albornoz F, Griffin JP et-al. Pharmacological inhibition and genetic deficiency of plasminogen activator inhibitor-1 attenuates angiotensin II/salt-induced aortic remodeling. Arterioscler. Thromb. Vasc. Biol. 2005;25 (2): 365-71. doi:10.1161/01.ATV.0000152356.85791.52Pubmed citation

2. Sejima T, Madoiwa S, Mimuro J et-al. Protection of plasminogen activator inhibitor-1-deficient mice from nasal allergy. J. Immunol. 2005;174 (12): 8135-43. J. Immunol. (link)Pubmed citation

3. Vayalil PK, Olman M, Murphy-ullrich JE et-al. Glutathione restores collagen degradation in TGF-beta-treated fibroblasts by blocking plasminogen activator inhibitor-1 expression and activating plasminogen. Am. J. Physiol. Lung Cell Mol. Physiol. 2005;289 (6): L937-45. doi:10.1152/ajplung.00150.2005Pubmed citation

4. De taeye BM, Novitskaya T, Gleaves L et-al. Bone marrow plasminogen activator inhibitor-1 influences the development of obesity. J. Biol. Chem. 2006;281 (43): 32796-805. doi:10.1074/jbc.M606214200Pubmed citation

5. Omasu F, Oda T, Yamada M et-al. Effects of pioglitazone and candesartan on renal fibrosis and the intrarenal plasmin cascade in spontaneously hypercholesterolemic rats. Am. J. Physiol. Renal Physiol. 2007;293 (4): F1292-8. doi:10.1152/ajprenal.00232.2007Pubmed citation

6. Vayalil PK, Iles KE, Choi J et-al. Glutathione suppresses TGF-beta-induced PAI-1 expression by inhibiting p38 and JNK MAPK and the binding of AP-1, SP-1, and Smad to the PAI-1 promoter. Am. J. Physiol. Lung Cell Mol. Physiol. 2007;293 (5): L1281-92. doi:10.1152/ajplung.00128.2007Free text at pubmedPubmed citation

7. Kuramoto E, Nishiuma T, Kobayashi K et-al. Inhalation of urokinase-type plasminogen activator reduces airway remodeling in a murine asthma model. Am. J. Physiol. Lung Cell Mol. Physiol. 2009;296 (3): L337-46. doi:10.1152/ajplung.90434.2008Pubmed citation

8. Wheaton AK, Velikoff M, Agarwal M, et al. The Vitronectin RGD motif regulates TGF? Induced Alveolar Epithelial Cell Apoptosis. Am J Physiol Lung Cell Mol Physiol. 2016;:ajplung.00424.2015.

9. Cui H, Ge J, Xie N, et al. miR-34a promotes fibrosis in aged lungs by inducing alveolar epithelial dysfunctions. Am J Physiol Lung Cell Mol Physiol. 2016;:ajplung.00335.2016. Link to article.