Prekallikrein, Human Plasma

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Product Description

Prekallikrein, Human Plasma</H3
Zymogen precursor of the plasma serine protease kallikrein. Human Prekallikrein is a single chain gamma globulin glycoprotein that participates in the early phase of contact activation, kinin formation and fibrinolysis. Prekallikrein purity is >95percent by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol. Prepared from plasma found negative by FDA accepted methods for Anti-HIV1/2, Anti-HTLV I & II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors are screened for CJD (Creutzfeldt-Jakob Disease).

Gene ID: 3818
Swiss-Prot/UniProt ID: P03952

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1. Dementiev A, Silva A, Yee C, et al. Structures of human plasma β-factor XIIa cocrystallized with potent inhibitors. Blood Adv. 2018;2(5):549-558. Link to article