Phe-Phe-Arg-Chloromethylketone

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Phe-Phe-Arg-Chloromethylketone

Phe-Phe-Arg-CMK (FFRCK). Potent and specific irreversible inhibitor of plasma and glandular kallikreins. Inhibits the cleavage of atrial naturiuretic peptide (ANP 1-126) by kallikreins. Also inhibits adrenal kininogenase, a kallikrein-like enzyme. Also known as PPACK2.

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