Mouse Protein C, C-terminal 8x His tag
This high quality recombinant protein is an excellent replacement for plasma derived mouse Protein C which is no longer available. Incubation with thrombin generates Activated Protein C (APC) with activity on chromogenic substrate. Recombinantly produced in HEK cell culture and purified by a combination of chelated metal affinity and conventional chromatography. Contains a 8X-Histidine tag at C terminus for purification. The protein purity is determined by SDS-PAGE and shows total reduction upon incubation with 2-mercaptoethanol. Protein C is activated in vivo to the serine protease APC by alpha-thrombin or the complex of alpha-thrombin/thrombomodulin. APC is a potent anticoagulant through the selective inactivation of Factors Va and VIIIa.
Gene ID: 19123
Swiss-Prot/UniProt ID: P33587