Mouse plasmin



Product Description

Mouse plasmin

Prepared from plasminogen by activation with immobilized human uPA. 100 percent functionally active plasmin is purified from the activation reaction by immobilized SBTI. Plasmin will undergo rapid auto proteolysis in the absence of benzamidine and should be used quickly once thawed. Aliquot to avoid freeze-thaw cycles.

Gene ID: 18815
Swiss-Prot/UniProt ID: P20918

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1. Bruno MA, Cuello AC. Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade. Proc. Natl. Acad. Sci. U.S.A. 2006;103 (17): 6735-40. doi:10.1073/pnas.0510645103Free text at pubmedPubmed citation

2. Van den broeck T, Stevenaert F, Taveirne S et-al. Ly49E-dependent inhibition of natural killer cells by urokinase plasminogen activator. Blood. 2008;112 (13): 5046-51. doi:10.1182/blood-2008-06-164350Pubmed citation

3. Magnussen SN, Hadler-olsen E, Costea DE, et al. Cleavage of the urokinase receptor (uPAR) on oral cancer cells: regulation by transforming growth factor – β1 (TGF-β1) and potential effects on migration and invasion. BMC Cancer. 2017;17(1):350. Link to article

4. Andersen LM, Wind T, Hansen HD, Andreasen PA. A cyclic peptidylic inhibitor of murine urokinase-type plasminogen activator: changing species specificity by substitution of a single residue. Biochem J. 2008;412(3):447-57. Link to article

5. Diaz A, Jeanneret V, Merino P, Mccann P, Yepes M. Tissue-type plasminogen activator regulates p35-mediated Cdk5 activation in the postsynaptic terminal. J Cell Sci. 2019;132(5). Link to article