Mouse PAI-1 (stable mutant)

$695$1,300

Clear
SKU: MPAI-I91L Categories: ,

Product Description

Using information obtained from the studies which produced stabilized human PAI-1 (CPAI) we have available a form of mouse PAI-1 that has a single conservative mutation (Isoleucine 91 to Leucine).

Gene ID: 18787
Swiss-Prot/UniProt ID: P22777

View sample datasheet
View sample certificate of analysis
View material safety data sheet
Ask a question about this product

Additional Information

Purity

Source

Molecular Weight

Extinction Coefficient

Species

Storage

Shipping Conditions

Expiration

Form

Buffer

Sample Size

Sample Concentration

Sample Volume

Gene Name

Gene ID

UniProt ID

1. Arndt PG, Young SK, Worthen GS. Regulation of lipopolysaccharide-induced lung inflammation by plasminogen activator Inhibitor-1 through a JNK-mediated pathway. J. Immunol. 2005;175 (6): 4049-59. J. Immunol. (link)Pubmed citation

2. Vayalil PK, Olman M, Murphy-ullrich JE et-al. Glutathione restores collagen degradation in TGF-beta-treated fibroblasts by blocking plasminogen activator inhibitor-1 expression and activating plasminogen. Am. J. Physiol. Lung Cell Mol. Physiol. 2005;289 (6): L937-45. doi:10.1152/ajplung.00150.2005Pubmed citation

3. Arndt PG, Young SK, Poch KR et-al. Systemic inhibition of the angiotensin-converting enzyme limits lipopolysaccharide-induced lung neutrophil recruitment through both bradykinin and angiotensin II-regulated pathways. J. Immunol. 2006;177 (10): 7233-41. J. Immunol. (link)Pubmed citation

4. Sashindranath M, Sales E, Daglas M et-al. The tissue-type plasminogen activator-plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans. Brain. 2012;135 (Pt): 3251-64. doi:10.1093/brain/aws178Free text at pubmedPubmed citation