Kininogen, LMW, Human Plasma


SKU: HK-LMW Categories: ,

Product Description

Kininogen, LMW, Human Plasma

Low Molecular Weight Kininogen is involved in blood pressure regulation since it is an endogenous protein substrate for tissue kallikrein. Proteolytic cleavage by kallikrein releases vasoactive bradykinin from LMW kininogen. In addition, LMW kininogen, like HMW kininogen, is a major extracellular cysteine protease inhibitor. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.

Gene ID: 3827
Swiss-Prot/UniProt ID: P01042

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Gene ID

UniProt ID

1. Yamamoto-Imoto, H. A novel detection method of cleaved plasma high-molecular-weight kininogen reveals its correlation with Alzheimer’s pathology and cognitive impairment. Link to article