Kininogen Knockout Mice
This Kininogen (KNG1) knockout mouse model was created by targeted disruption of KNG1 using programed nuclease. Mutations are confirmed by PCR genotyping and Sanger sequencing. Heterozygous mice are in breeding now and homozygous mice will be available soon. This KNG1 KO mouse model will be useful for intrinsic/contact pathway coagulation research.
Strain Background: C57BL/6
Synonyms: KNG, Fitzgerald Factor, Alpha-2-thiol Proteinase Inhibitor
Genomic Target: Exon 4
Mutation: 2 base pair deletion
Our mutant mice are from an ongoing colony made in-house at our state of the art facility in the U.S.A and available immediately. No waiting for cryo recovery or costly breeding.
We also provide custom Mouse Model projects and offer FREE consulting services from our expert scientific staff along with very competitive pricing. Click here to inquire.