Inhibitory mouse monoclonal to human PAI-1 clone 8H9D4

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Product Description

Inhibitory mouse monoclonal to human PAI-1 clone 8H9D4

Inhibitory monoclonal antibody to human and porcine PAI-1. Does not cross-react with mouse or rat. It binds to the axis connecting Arg300, Gln303 and Arg305 interfering with the final step of covalent complex formation. MA-8H9D4 shifts the reaction to the substrate pathway without decreasing the rate-limiting constant for reactive center loop insertion by tPA.

Gene ID: 5054
Swiss-Prot/UniProt ID: P05121

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