Immobilized porcine pepsin

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Immobilized porcine pepsin

Immobilized porcine pepsin is ideal for digestion of IgG to generate F(ab’)2 fragments. Pepsin is a non-specific endopeptidase that cleaves peptide bonds preferentially at aromatic residues such as tyrosines and phenylalanine. It generally does not cleave at alanine, glycine or valine residues.

Gene ID: 396892
Swiss-Prot/UniProt ID: A1YM35

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1. Florova G, Karandashova S, Declerck PJ et-al. Remarkable stabilization of plasminogen activator inhibitor 1 in a “molecular sandwich” complex. Biochemistry. 2013;52 (27): 4697-709. doi:10.1021/bi400470sFree text at pubmedPubmed citation