Human Thrombin Activatable Fibrinolysis Inhibitor

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SKU: TAFI Categories: ,

Product Description

Thrombin Activatable Fibrinolysis Inhibitor (TAFI), also known as plasma procarboxypeptidase-B and carboxypeptidase-U, is a single chain glycoprotein that is cleaved by thrombin, plasmin and trypsin. TAFI is purified from normal human plasma using immunoaffinity and ion-exchange chromatography. Activated TAFI cleaves C-terminal lysines on fibrin and cell surfaces resulting in down-regulation of fibrinolysis by reducing the number of plasminogen and tPA binding sites on fibrin.

Gene ID: 1361
Swiss-Prot/UniProt ID: Q96IY4

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