Human PAI-1 (wild type latent fraction)

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SKU: PAI-L Categories: ,

Product Description

<0.4percent active as determined by titration with HMW tc-urokinase and SDS PAGE. Latent PAI-1 is a useful control for experiments when used in conjunction with the active from. Gene ID: 5054
Swiss-Prot/UniProt ID: P05121

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1. Minor KH, Schar CR, Blouse GE et-al. A mechanism for assembly of complexes of vitronectin and plasminogen activator inhibitor-1 from sedimentation velocity analysis. J. Biol. Chem. 2005;280 (31): 28711-20. doi:10.1074/jbc.M500478200Free text at pubmedPubmed citation

2. Wu J, Peng L, Mcmahon GA et-al. Recombinant plasminogen activator inhibitor-1 inhibits intimal hyperplasia. Arterioscler. Thromb. Vasc. Biol. 2009;29 (10): 1565-70. doi:10.1161/ATVBAHA.109.189514Free text at pubmedPubmed citation

3. Fjellström O, Deinum J, Sjögren T et-al. Characterization of a small molecule inhibitor of plasminogen activator inhibitor type 1 that accelerates the transition into the latent conformation. J. Biol. Chem. 2013;288 (2): 873-85. doi:10.1074/jbc.M112.371732Free text at pubmedPubmed citation