Human PAI-1 stable mutant NBD labeled at the scissile bond of the reactive loop

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Product Description

Human PAI-1 stable mutant NBD labeled at the scissile bond of the reactive loop

Mutagenesis of the P1′ methionine residue (Met347) at the P1-P1′ scissile bond of human PAI-1 stable mutant (K154T, Q319L, M354I and N150H) to cysteine followed by incorporation of NBD has produced a reporter PAI-1 with extended half life. The properties of this interesting new reagent have not been fully characterized.

Gene ID: 5054
Swiss-Prot/UniProt ID: P05121

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