Human PAI-1 (substrate form – P14 Arginine mutant)

$695$1,140

Clear
SKU: HPAI-T333R Categories: ,

Product Description

Human PAI-1 (substrate form – P14 Arginine mutant)

A single substitution at position P14 in the reactive center loop produces a PAI-1 that becomes a substrate for proteinases rather than an inhibitor. Reactive center loop insertion follows protease cleavage and the PAI-1 loses vitronectin binding properties. This molecule is useful for mechanistic studies.
References
1. Lawrence, D.A. et al. (2000) J. Biol. Chem. 275:5839-5844.
2. Palmieri, D. et al. (2002) J. Biol. Chem. 277:40950-40957.

Gene ID: 5054
Swiss-Prot/UniProt ID: P05121

View sample datasheet
View sample certificate of analysis
View material safety data sheet
Ask a question about this product

Additional Information

Purity

Source

Molecular Weight

Extinction Coefficient

Species

Storage

Shipping Conditions

Expiration

Form

Buffer

Sample Size

Sample Concentration

Sample Volume

Gene Name

Gene ID

UniProt ID