Human alpha-thrombin

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SKU: HTHROM-A Categories: ,

Product Description

Human alpha-thrombin

Human alpha-thrombin is prepared from purified prothrombin. Purity is determined by SDS-PAGE analysis and activity is measured in a thrombin specific clotting assay, and compared to standardized NIH thrombin.

Gene ID: 2147
Swiss-Prot/UniProt ID: P00734

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1. Middendorp SJ, Wilbs J, Quarroz C, Calzavarini S, Angelillo-scherrer A, Heinis C. Peptide Macrocycle Inhibitor of Coagulation Factor XII with Subnanomolar Affinity and High Target Selectivity. J Med Chem. 2017;60(3):1151-1158. Link to article

2. Swedberg JE, Li CY, De veer SJ, Wang CK, Craik DJ. Design of Potent and Selective Cathepsin G Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold. J Med Chem. 2017;60(2):658-667. Link to article