Factor X Knockout Mice
This Factor X (F10) knockout mouse model was created by targeted disruption of F10 using programed nuclease. Mutations are confirmed by PCR genotyping, Sanger sequencing, and RT-PCR. Heterozygous mice are available for immediate shipment; homozygous F10 deficiency is an embryonic lethal condition. This FX KO mouse model will be useful for cardiovascular studies.
Strain Background: C57BL6/SJL
Protein: Coagulation Factor X
Synonyms: FX, Stuart-Prower Factor
Genomic Target: Exon 2
Mutation: 14 base pair deletion
Our mutant mice are from an ongoing colony made in-house at our state of the art facility in the U.S.A and available immediately. No waiting for cryo recovery or costly breeding.
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